Dr Andrea Malaspina is a Reader in Clinical Neurology and Consultant Neurologist with research interests in neuromuscular and motor cell disorders. He is the Co-Director of a MND Care and Research Centre covering a North-East London and Essex referral population and responsible for MND research in the North-Thames LCRN. He leads a multi-disciplinary neurodegenerative biomarkers research group within the Neuroscience and Trauma Centre, Blizard Institute. His research focus is the identification and characterization in accessible tissues and bio fluids of biological signals whose expression, composition and conformation reflect the risk of developing a neurodegenerative pathology, predict its rate of progression and response to treatment. This multi-modal approach is applied to motor neuron disease to unravel the biological mechanisms behind onset and propagation of this neurodegenerative process. He has established and developed large bio banking projects for neurodegenerative disorders and for MND, including the ALS biomarkers study and A Multicentre Biomarker Resource Strategy in ALS (AMBRoSIA), combining longitudinal collection and novel concepts for storage and biochemical assay optimization.